ARG45682
anti-ORP8 antibody
anti-ORP8 antibody for Flow cytometry,ICC/IF,Western blot and Human
概述
产品描述 | Rabbit Polyclonal antibody recognizes ORP8 |
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反应物种 | Hu |
应用 | FACS, ICC/IF, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | ORP8 |
抗原物种 | Human |
抗原 | Recombinant protein containing to human ORP8. |
偶联标记 | Un-conjugated |
別名 | OSBPL8; Oxysterol Binding Protein Like 8; OSBP10; ORP8; MSTP120; MST120; Oxysterol-Binding Protein-Related Protein 8; OSBP-Related Protein 8; Oxysterol Binding Protein-Like 8; KIAA1451; ORP-8 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Affinity purified |
缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
稳定剂 | 4% Trehalose |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 |
Swiss-port # Q9BZF1 Human Oxysterol-binding protein-related protein 8 |
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基因名称 | OSBPL8 |
全名 | Oxysterol Binding Protein Like 8 |
背景介绍 | This gene encodes a member of a family of proteins containing an N-terminal pleckstrin homology domain and a highly conserved C-terminal oxysterol-binding protein-like sterol-binding domain. It binds mutliple lipid-containing molecules, including phosphatidylserine, phosphatidylinositol 4-phosphate (PI4P) and oxysterol, and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
生物功能 | Lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane: specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum. Binds phosphatidylserine and PI4P in a mutually exclusive manner. [UniProt] |
细胞定位 | Endoplasmic reticulum; Membrane; Nucleus. [UniProt] |
预测分子量 | 101 kDa |
翻译后修饰 | Acetylation; Phosphoprotein. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG45682 anti-ORP8 antibody ICC/IF image
Immunofluorescence: Hela stained with ARG45682 anti-ORP8 antibody at 5 μg/ml dilution.
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ARG45682 anti-ORP8 antibody WB image
Western blot: 293T stained with ARG45682 anti-ORP8 antibody at 0.5 μg/ml dilution.
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ARG45682 anti-ORP8 antibody FACS image
Flow Cytometry: HepG2 stained with ARG45682 anti-ORP8 antibody at 1 µg/10^6 cells dilution.