ARG64804

anti-ORAI1 / CRACM1 antibody

anti-ORAI1 / CRACM1 antibody for Western blot and Human

Immune System antibody; Signaling Transduction antibody

概述

产品描述 Goat Polyclonal antibody recognizes ORAI1 / CRACM1
反应物种 Hu
预测物种 Dog, Pig
应用 WB
宿主 Goat
克隆 Polyclonal
同位型 IgG
靶点名称 ORAI1 / CRACM1
抗原物种 Human
抗原 C-KKQPGQPRPTSKP
偶联标记 Un-conjugated
別名 Protein orai-1; CRACM1; Transmembrane protein 142A; IMD9; ORAT1; Calcium release-activated calcium channel protein 1; TAM2; TMEM142A

应用说明

应用建议
应用 推荐稀释比
WB0.03 - 0.1 µg/ml
应用说明 WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purified from goat serum by antigen affinity chromatography.
缓冲液 Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 0.5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 84876 Human ORAI1

Swiss-port # Q96D31 Human Calcium release-activated calcium channel protein 1

背景介绍 The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1). [provided by RefSeq, Sep 2011]
研究领域 Immune System antibody; Signaling Transduction antibody
预测分子量 33 kDa
翻译后修饰 N-glycosylated.
Ubiquitinated.
Cys-195 is oxidated, leading to inactivate channel activity.

检测图片 (2) Click the Picture to Zoom In

  • ARG64804 anti-ORAI1 / CRACM1 antibody WB image

    Western Blot: Human Placenta lysate (35 µg protein in RIPA buffer) stained with ARG64804 anti-ORAI1 / CRACM1 antibody at 0.03 µg/ml dilution.

  • ARG64804 anti-ORAI1 / CRACM1 antibody WB image

    Western blot: 35 µg of Human skin lysate (in RIPA buffer) stained with ARG64804 anti-ORAI1 / CRACM1 antibody at 0.1 µg/ml dilution and incubated at RT for 1 hour.