ARG45313
anti-OCRL antibody
anti-OCRL antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Polyclonal antibody recognizes OCRL |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | OCRL |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human OCRL. |
| 偶联标记 | Un-conjugated |
| 別名 | OCRL; OCRL Inositol Polyphosphate-5-Phosphatase; OCRL1; Dent-2; Phosphatidylinositol 3,4,5-Triphosphate 5-Phosphatase; Inositol Polyphosphate 5-Phosphatase OCRL-1; Inositol Polyphosphate 5-Phosphatase OCRL; Lowe Oculocerebrorenal Syndrome Protein; Oculocerebrorenal Syndrome Of Lowe; OCRL-1; Phosphatidylinositol Polyphosphate 5-Phosphatase; Dent Disease 2; EC 3.1.3.36; EC 3.1.3.56; EC 3.1.3.86; INPP5F; DENT2; NPHL2; LOCR |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 104 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q01968 Human Inositol polyphosphate 5-phosphatase OCRL-1 |
|---|---|
| 基因名称 | OCRL |
| 全名 | OCRL Inositol Polyphosphate-5-Phosphatase |
| 背景介绍 | This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] GeneCards Summary for OCRL Gene |
| 生物功能 | Catalyzes the hydrolysis of the 5-position phosphate of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol-3,4,5-bisphosphate (PtdIns(3,4,5)P3), with the greatest catalytic activity towards PtdIns(4,5)P2 . [UniProt] |
| 细胞定位 | Cell projection; Cilium; Coated pit; Cytoplasmic vesicle; Endosome; Golgi apparatus; Lysosome; Membrane. [UniProt] |
| 预测分子量 | 104 kDa |
检测图片 (3) Click the Picture to Zoom In
-
ARG45313 anti-OCRL antibody IHC-P image
Immunohistochemistry: Human colon adenocarcinoma stained with ARG45313 anti-OCRL antibody at 2 μg/ml dilution.
-
ARG45313 anti-OCRL antibody ICC/IF image
Immunofluorescence: A549 stained with ARG45313 anti-OCRL antibody at 5 ug/ml dilution.
-
ARG45313 anti-OCRL antibody WB image
Western blot: 293T and Hela stained with ARG45313 anti-OCRL antibody at 0.5 μg/ml dilution.
