ARG40238
anti-OB Cadherin antibody
anti-OB Cadherin antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes OB Cadherin |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | OB Cadherin |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 637-796 of Human OB Cadherin (NP_001788.2). |
| 偶联标记 | Un-conjugated |
| 別名 | CDHOB; OB-cadherin; Osteoblast cadherin; Cadherin-11; OB; OSF-4; CAD11 |
应用说明
| 预测反应性说明 | Rat | ||||
|---|---|---|---|---|---|
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse spleen and SKOV3 | ||||
| 实际分子量 | 110 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CDH11 |
| 全名 | cadherin 11, type 2, OB-cadherin (osteoblast) |
| 背景介绍 | This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008] |
| 生物功能 | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. [UniProt] |
| 细胞定位 | Cell membrane, Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 88 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG40238 anti-OB Cadherin antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse brain stained with ARG40238 anti-OB Cadherin antibody at 1:100 dilution.
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ARG40238 anti-OB Cadherin antibody WB image
Western blot: 25 µg of SKOV3 cell lysate stained with ARG40238 anti-OB Cadherin antibody at 1:3000 dilution.
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ARG40238 anti-OB Cadherin antibody WB image
Western blot: 25 µg of Mouse spleen lysate stained with ARG40238 anti-OB Cadherin antibody at 1:3000 dilution.
