ARG40720
anti-OAT3 / SLC22A8 antibody
anti-OAT3 / SLC22A8 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes OAT3 / SLC22A8 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Cow, Dog, Rb |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | OAT3 / SLC22A8 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the middle region of Human OAT3 / SLC22A8. (within the following region: PETLNQPLPETIEDLENWSLRAKKPKQEPEVEKASQRIPLQPHGPGLGSS) |
| 偶联标记 | Un-conjugated |
| 別名 | Organic anion transporter 3; Solute carrier family 22 member 8; hOAT3; OAT3 |
应用说明
| 预测反应性说明 | Predicted Homology Based On Immunogen Sequence: Cow: 79%; Dog: 79%; Mouse: 86%; Rabbit: 86% | ||||
|---|---|---|---|---|---|
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Human heart | ||||
| 实际分子量 | 65 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
| 抗菌剂 | 0.09% (w/v) Sodium azide |
| 稳定剂 | 2% Sucrose |
| 浓度 | Batch dependent: 0.5 - 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SLC22A8 |
| 全名 | solute carrier family 22 (organic anion transporter), member 8 |
| 背景介绍 | This gene encodes a protein involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, May 2010] |
| 生物功能 | Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone-3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA). [UniProt] |
| 细胞定位 | Basolateral cell membrane; Multi-pass membrane protein. Note=Localizes on the brush border membrane of the choroid epithelial cells. Localizes to the basolateral membrane of the proximal tubular cells. Localizes on the abluminal and possibly, luminal membrane of the brain capillary endothelial cells (BCEC) (By similarity). [UniProt] |
| 预测分子量 | 60 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG40720 anti-SLC22A8 antibody WB image
Western blot: Human heart lysate stained with ARG40720 anti-SLC22A8 antibody at 0.2 - 1 µg/ml dilution.
