ARG23976
anti-NrCAM antibody [S364-51]
anti-NrCAM antibody [S364-51] for Western blot and Mouse,Rat
概述
| 产品描述 | Mouse Monoclonal antibody [S364-51] recognizes NrCAM |
|---|---|
| 反应物种 | Ms, Rat |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | S364-51 |
| 同位型 | IgG2a |
| 靶点名称 | NrCAM |
| 抗原物种 | Mouse |
| 抗原 | Fusion protein corresponding to aa. 30-845 (extracellular domain) of Mouse NrCAM. |
| 偶联标记 | Un-conjugated |
| 別名 | Nr-CAM; Ng-CAM-related; hBravo; Neuronal surface protein Bravo; Neuronal cell adhesion molecule; NgCAM-related cell adhesion molecule |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | ~ 145 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.1% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.1% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NRCAM |
| 全名 | neuronal cell adhesion molecule |
| 背景介绍 | Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| 生物功能 | Cell adhesion, ankyrin-binding protein involved in neuron-neuron adhesion. May play a role in the molecular assembly of the nodes of Ranvier (By similarity). [UniProt] |
| 细胞定位 | Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Secreted. Note=Detected at nodes of Ranvier. [UniProt] |
| 预测分子量 | 144 kDa |
检测图片 (1) Click the Picture to Zoom In
-
ARG23976 anti-NrCAM antibody [S364-51] WB image
Western blot: 10 µg of Rat brain membrane lysate stained with ARG23976 anti-NrCAM antibody [S364-51] at 1:1000 dilution, for 1 hour at RT.
