ARG67268
anti-Nkx3.1 antibody [SQab30384]
anti-Nkx3.1 antibody [SQab30384] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Rabbit Monoclonal antibody [SQab30384] recognizes Nkx3.1. |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab30384 |
| 同位型 | IgG |
| 靶点名称 | Nkx3.1 |
| 抗原 | Synthetic peptide. |
| 偶联标记 | Un-conjugated |
| 別名 | NKX3-1; NK3 Homeobox 1; NKX3.1; BAPX2; NKX3A; Homeobox Protein NK-3 Homolog A; Homeobox Protein Nkx-3.1; NK3 Transcription Factor Related, Locus 1 (Drosophila); NK3 Transcription Factor Related, Locus 1; NK Homeobox (Drosophila), Family 3, A; NK3 Transcription Factor Homolog A; NK Homeobox, Family 3, A; NKX3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NKX3-1 |
| 全名 | NK3 Homeobox 1 |
| 背景介绍 | This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jan 2012] |
| 生物功能 | Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells. [Uniprot] |
| 细胞定位 | Nucleus. [Uniprot] |
| 预测分子量 | 26 kDa |
| 翻译后修饰 | Ubl conjugation. [Uniprot] |
检测图片 (1) Click the Picture to Zoom In
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ARG67268 anti-Nkx3.1 antibody [SQab30384] IHC-P image
Immunohistochemistry: Human Prostate stained with ARG67268 anti-Nkx3.1 antibody [SQab30384] at 1:100 dilution.
