ARG57559
anti-Neuropeptide Y antibody
anti-Neuropeptide Y antibody for IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Neuropeptide Y |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P |
| 特异性 | The sequence of immunogen for this Neuropeptide Y antibody is 100% homologous in Human, Mouse and Rat. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Neuropeptide Y |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the center region of Human Neuropeptide Y. (YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY) |
| 偶联标记 | Un-conjugated |
| 別名 | Pro-neuropeptide Y; Neuropeptide tyrosine; NPY; CPON; PYY4 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.025% Sodium azide and 2.5% BSA. |
| 抗菌剂 | 0.025% Sodium azide |
| 稳定剂 | 2.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NPY |
| 全名 | neuropeptide Y |
| 背景介绍 | This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014] |
| 生物功能 | NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. [UniProt] |
| 产品亮点 | Related news: Studying obesity and appetite control by quantifying orexigenic and anorexigenic hormones; |
| 预测分子量 | 11 kDa |
| 翻译后修饰 | The neuropeptide Y form is cleaved at Pro-30 by the prolyl endopeptidase FAP (seprase) activity (in vitro). [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG57559 anti-Neuropeptide Y antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Mouse brain tissue stained with ARG57559 anti-Neuropeptide Y antibody.
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ARG57559 anti-Neuropeptide Y antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Rat brain tissue stained with ARG57559 anti-Neuropeptide Y antibody.
