ARG59839
anti-Nesprin 3 antibody
anti-Nesprin 3 antibody for ICC/IF,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Nesprin 3 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Nesprin 3 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 740-920 of Human Nesprin 3 (NP_689805.3). |
| 偶联标记 | Un-conjugated |
| 別名 | Nesp3; Nesprin-3; C14orf49; NET53; Nuclear envelope spectrin repeat protein 3 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | K-562 | ||||||
| 实际分子量 | 112 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SYNE3 |
| 全名 | spectrin repeat containing, nuclear envelope family member 3 |
| 生物功能 | Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells. [UniProt] |
| 细胞定位 | Nucleus outer membrane; Single-pass type IV membrane protein. Nucleus envelope. Rough endoplasmic reticulum. [UniProt] |
| 预测分子量 | 112 kDa |
| 翻译后修饰 | The disulfid bond with SUN1 or SUN2 is required for stability of the respective LINC complex under tensile forces. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG59839 anti-Nesprin 3 antibody WB image
Western blot: 25 µg of K-562 cell lysate stained with ARG59839 anti-Nesprin 3 antibody at 1:3000 dilution.
