ARG45824
anti-Nebulette antibody
anti-Nebulette antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Nebulette |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Nebulette |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human Nebulette. |
| 偶联标记 | Un-conjugated |
| 別名 | NEBL; Nebulette; LNEBL; BA165O3.1; C10orf113; LASP2; Actin-Binding Z-Disk Protein; LIM And SH3 Protein 2; LIM-Nebulette; Chromosome 10 Open Reading Frame 113 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 126 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O76041 Human Nebulette Swiss-port # Q9DC07 Mouse LIM zinc-binding domain-containing Nebulette |
|---|---|
| 基因名称 | NEBL |
| 全名 | Nebulette |
| 背景介绍 | This gene encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] |
| 生物功能 | Binds to actin and plays an important role in the assembly of the Z-disk. May functionally link sarcomeric actin to the desmin intermediate filaments in the heart muscle sarcomeres. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 126 kDa |
| 翻译后修饰 | Methylation. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG45824 anti-Nebulette antibody IHC-P image
Immunohistochemistry: Mouse heart stained with ARG45824 anti-Nebulette antibody at 2 μg/ml dilution.
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ARG45824 anti-Nebulette antibody IHC-P image
Immunohistochemistry: Rat heart stained with ARG45824 anti-Nebulette antibody at 2 μg/ml dilution.
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ARG45824 anti-Nebulette antibody WB image
Western blot: Rat brain stained with ARG45824 anti-Nebulette antibody at 0.5 μg/ml dilution.
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ARG45824 anti-Nebulette antibody WB image
Western blot: Mouse brain stained with ARG45824 anti-Nebulette antibody at 0.5 μg/ml dilution.
