ARG40171
anti-Natriuretic Peptide Receptor C (NPR C) antibody
anti-Natriuretic Peptide Receptor C (NPR C) antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Goat Polyclonal antibody recognizes Natriuretic Peptide Receptor C (NPR C) |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Cow, Dog, Pig |
| 应用 | IHC-P, WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Natriuretic Peptide Receptor C (NPR C) |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the C-terminus of Human Natriuretic Peptide Receptor C. (C-HRELREDSIRSHFS, NP_000899.1) |
| 偶联标记 | Un-conjugated |
| 別名 | GUCY2B; ANPRC; C5orf23; Atrial natriuretic peptide receptor 3; NPR-C; NPRC; Atrial natriuretic peptide receptor type C; Atrial natriuretic peptide clearance receptor; ANPR-C; ANP-C |
应用说明
| 应用建议 |
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| 应用说明 | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Microwaved or steamed tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P17342 Human Atrial natriuretic peptide receptor 3 |
|---|---|
| 基因名称 | NPR3 |
| 全名 | natriuretic peptide receptor 3 |
| 背景介绍 | This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011] |
| 生物功能 | Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity. [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 60 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG40171 anti-Natriuretic Peptide Receptor C (NPR C) antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human kidney tissue. Antigen Retrieval: Microwaved tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG40171 anti-Natriuretic Peptide Receptor C (NPR C) antibody at 2 µg/ml dilution followed by HRP-staining.
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ARG40171 anti-Natriuretic Peptide Receptor C (NPR C) antibody WB image
Western blot: 35 µg of Human placenta lysate (in RIPA buffer) stained with ARG40171 anti-Natriuretic Peptide Receptor C (NPR C) antibody at 1 µg/ml dilution and incubated at RT for 1 hour.
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ARG40171 anti-Natriuretic Peptide Receptor C (NPR C) antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human prostate tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG40171 anti-Natriuretic Peptide Receptor C (NPR C) antibody at 10 µg/ml dilution followed by AP-staining.
