ARG46317

anti-Nanos3 antibody

anti-Nanos3 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes Nanos3
反应物种 Hu, Ms, Rat
应用 IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 Nanos3
抗原物种 Human
抗原 A 16 amino acid synthetic peptide within the last 50 amino acids of human Nanos3.
偶联标记 Un-conjugated
別名 nanos homolog 3 (Drosophila); Nanos3; NOS3; NANOS1L; NOS3; Nanos homolog 3; NOS-3

应用说明

应用建议
应用 推荐稀释比
IHC-PAssay-dependent
WBAssay-dependent
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量 20 kDa

属性

形式 Liquid
纯化 Affinity chromatography purified
缓冲液 PBS and 0.02% Sodium azide.
抗菌剂 0.02% Sodium azide
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -367°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 244551 Mouse NANOS3

GeneID: 342977 Human NANOS3

Swiss-port # P60323 Human Nanos homolog 3

Swiss-port # P60324 Mouse Nanos homolog 3

基因名称 NANOS3
全名 nanos homolog 3 (Drosophila)
背景介绍 Enables enzyme activator activity. Involved in germ cell development; mRNA destabilization; and negative regulation of translation. Located in cytosol; nucleoplasm; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
生物功能 Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis. [UniProt]
细胞定位 Cytoplasm; Nucleus. [UniProt]
预测分子量 19 kDa