ARG45511
anti-NXN / NRX antibody
anti-NXN / NRX antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NXN / NRX |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NXN / NRX |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human NXN / NRX. |
| 偶联标记 | Un-conjugated |
| 別名 | NXN; Nucleoredoxin; NRX; EC 1.8.1.8 47; FLJ12614; Nucleoredoxin 1; TRG-4; RRS2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 48 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NXN |
| 全名 | Nucleoredoxin |
| 背景介绍 | This gene encodes a member of the thioredoxin superfamily, a group of small, multifunctional redox-active proteins. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. The encoded protein acts a redox-dependent regulator of the Wnt signaling pathway and is involved in cell growth and differentiation. [provided by RefSeq, Sep 2015] |
| 生物功能 | Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A). [UniProt] |
| 细胞定位 | Cytoplasm; Nucleus. [UniProt] |
| 预测分子量 | 48 kDa |
| 翻译后修饰 | Acetylation. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG45511 anti-NXN / NRX antibody IHC-P image
Immunohistochemistry: Human placenta stained with ARG45511 anti-NXN / NRX antibody at 2 μg/ml dilution.
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ARG45511 anti-NXN / NRX antibody ICC/IF image
Immunofluorescence: Caco-2 stained with ARG45511 anti-NXN / NRX antibody at 5 μg/ml dilution.
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ARG45511 anti-NXN / NRX antibody WB image
Western blot: Caco-2 stained with ARG45511 anti-NXN / NRX antibody at 0.5 μg/ml dilution.
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ARG45511 anti-NXN / NRX antibody FACS image
Flow Cytometry: SiHa stained with ARG45511 anti-NXN / NRX antibody at 1 µg/10^6 cells dilution.
