ARG54088
anti-NUP98 antibody
anti-NUP98 antibody for Immunoprecipitation,Western blot and Human
Gene Regulation antibody; Signaling Transduction antibody
概述
| 产品描述 | Mouse Monoclonal antibody recognizes NUP98 |
|---|---|
| 反应物种 | Hu |
| 应用 | IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | NUP98 |
| 抗原物种 | Human |
| 抗原 | Purified recombinant human NUP98 protein fragments expressed in E.coli. |
| 偶联标记 | Un-conjugated |
| 別名 | NUP196; Nuclear pore complex protein Nup98-Nup96; ADIR2; Nup98; Nup96; NUP96; 98 kDa nucleoporin; Nucleoporin Nup98; Nucleoporin Nup96; 96 kDa nucleoporin |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 98 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.1M Tris-Glycine (pH 7.4), 150 mM NaCl, 0.2% Sodium azide and 50% Glycerol |
| 抗菌剂 | 0.2% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P52948 Human Nuclear pore complex protein Nup98-Nup96 |
|---|---|
| 基因名称 | NUP98 |
| 全名 | nucleoporin 98kDa |
| 背景介绍 | Nup98 and Nup96 play a role in the bidirectional transport across the nucleoporin complex (NPC). The repeat domain in Nup98 has a direct role in the transport. |
| 生物功能 | Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Nup98 and Nup96 are involved in the bidirectional transport across the NPC. May anchor NUP153 and TPR to the NPC. [UniProt] |
| 细胞定位 | Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. |
| 研究领域 | Gene Regulation antibody; Signaling Transduction antibody |
| 预测分子量 | 198 kDa |
| 翻译后修饰 | Isoform 1 to isoform 4 are autoproteolytically cleaved to yield Nup98 and Nup96 or Nup98 only, respectively (PubMed:10087256, PubMed:20407419, PubMed:12191480, PubMed:18287282). Cleaved Nup98 is necessary for the targeting of Nup98 to the nuclear pore and the interaction with Nup96 (PubMed:20407419, PubMed:12191480). Proteolytically degraded after poliovirus (PV) infection; degradation is partial and NCP- and TPR-binding domains withstand degradation. |
检测图片 (2) Click the Picture to Zoom In
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ARG54088 anti-NUP98 antibody WB image
Western blot: HeLa cell lysate stained with ARG54088 anti-NUP98 antibody at 1:1000 dilution.
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ARG54088 anti-NUP98 antibody IP image
Immunoprecipitation: HeLa cell lysates were immunoprecipitated and stained with ARG54088 anti-NUP98 antibody.
