ARG44113
anti-NUMA1 antibody
anti-NUMA1 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat,Monkey
概述
| 产品描述 | Rabbit Polyclonal recognizes NUMA1 |
|---|---|
| 反应物种 | Hu, Ms, Rat, Mk |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NUMA1 |
| 抗原物种 | Human |
| 抗原 | Human NUMA1 recombinant protein (Position: M1-E1954). |
| 偶联标记 | Un-conjugated |
| 別名 | NUMA1; Nuclear Mitotic Apparatus Protein 1; NUMA; Nuclear Matrix Protein-22; SP-H Antigen; NMP-22; Centrophilin Stabilizes Mitotic Spindle In Mitotic Cells; Nuclear Mitotic Apparatus Protein; Structural Nuclear Protein; NuMA Protein; NMP22 |
应用说明
| 应用建议 |
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| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q14980 Human Nuclear mitotic apparatus protein 1 |
|---|---|
| 基因名称 | NUMA1 |
| 全名 | Nuclear Mitotic Apparatus Protein 1 |
| 背景介绍 | This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants. |
| 生物功能 | Microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignement and the segregation of chromosomes during mitotic cell division. |
| 细胞定位 | Cell membrane, Chromosome, Cytoplasm, Cytoskeleton, Membrane, Microtubule, Nucleus |
| 预测分子量 | 238 kDa |
| 翻译后修饰 | Acetylation, ADP-ribosylation, Glycoprotein, Isopeptide bond, Lipoprotein, Phosphoprotein, Ubl conjugation |
检测图片 (8) Click the Picture to Zoom In
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ARG44113 anti-NUMA1 antibody IHC-P image
Immunohistochemistry: Human acinar adenocarcinoma of prostate stained with ARG44113 anti-NUMA1 antibody at 2 μg/ml dilution.
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ARG44113 anti-NUMA1 antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG44113 anti-NUMA1 antibody at 5 μg/ml dilution.
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ARG44113 anti-NUMA1 antibody WB image
Western blot: Hela, COS-7, MCF-7 and SH-SY5Y stained with ARG44113 anti-NUMA1 antibody at 0.5 μg/ml dilution.
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ARG44113 anti-NUMA1 antibody FACS image
Flow Cytometry: RT4 stained with ARG44113 anti-NUMA1 antibody at 1 µg/10^6 cells dilution.
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ARG44113 anti-NUMA1 antibody WB image
Western blot: PC-12 stained with ARG44113 anti-NUMA1 antibody at 0.5 μg/ml dilution.
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ARG44113 anti-NUMA1 antibody WB image
Western blot: NIH/3T3 stained with ARG44113 anti-NUMA1 antibody at 0.5 μg/ml dilution.
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ARG44113 anti-NUMA1 antibody IHC-P image
Immunohistochemistry: Human breast cancer stained with ARG44113 anti-NUMA1 antibody at 2 μg/ml dilution.
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ARG44113 anti-NUMA1 antibody IHC-P image
Immunohistochemistry: Human esophageal squamous carcinoma stained with ARG44113 anti-NUMA1 antibody at 2 μg/ml dilution.
