ARG44111
anti-NUF2 antibody
anti-NUF2 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal recognizes NUF2 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NUF2 |
| 抗原物种 | Human |
| 抗原 | Human NUF2 recombinant protein (Position: M1-Q297). |
| 偶联标记 | Un-conjugated |
| 別名 | NUF2; NUF2 Component Of NDC80 Kinetochore Complex; NUF2R; CT106; CDCA1; NDC80 Kinetochore Complex Component NUF2; Cell Division Cycle-Associated Protein 1; Cell Division Cycle Associated 1; Cancer/Testis Antigen 106; Kinetochore Protein Nuf2; HNuf2R; HsNuf2; HNuf2; NUF2, NDC80 Kinetochore Complex Component, Homolog (S. Cerevisiae); NUF2, NDC80 Kinetochore Complex Component, Homolog |
应用说明
| 应用建议 |
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| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NUF2 |
| 全名 | NUF2 Component Of NDC80 Kinetochore Complex |
| 背景介绍 | This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. |
| 生物功能 | Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. |
| 细胞定位 | Centromere, Chromosome, Kinetochore, Nucleus |
| 预测分子量 | 54 kDa |
| 翻译后修饰 | Acetylation, Phosphoprotein |
检测图片 (1) Click the Picture to Zoom In
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ARG44111 anti-NUF2 antibody WB image
Western blot: A431 and U251 stained with ARG44111 anti-NUF2 antibody at 0.5 μg/ml dilution.
