ARG44289
anti-NSMase2 antibody
anti-NSMase2 antibody for ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NSMase2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NSMASE2 |
| 抗原物种 | Human |
| 抗原 | NSMase2 synthetic peptide |
| 偶联标记 | Un-conjugated |
| 別名 | SMPD3; Sphingomyelin Phosphodiesterase 3; Neutral Sphingomyelinase II; NSMASE2; Neutral Sphingomyelinase 2; NSMase-2; Sphingomyelin Phosphodiesterase 3, Neutral Membrane (Neutral Sphingomyelinase II); EC 3.1.4.12; NSMase2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Antigen Affinity Purified |
| 缓冲液 | PBS with 1 mg/ml BSA, 0.05% Sodium azide and 50% glycerol |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 1 mg/ml BSA and 50% glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SMPD3 |
| 全名 | Sphingomyelin Phosphodiesterase 3 |
| 背景介绍 | Predicted to enable phosphatidic acid binding activity; phosphatidylserine binding activity; and sphingomyelin phosphodiesterase activity. Predicted to be involved in positive regulation of exosomal secretion and sphingomyelin metabolic process. Predicted to act upstream of or within several processes, including animal organ development; enzyme linked receptor protein signaling pathway; and sphingolipid metabolic process. Predicted to be located in Golgi apparatus and plasma membrane. Predicted to be active in cytoplasm. Biomarker of pulmonary emphysema. |
| 生物功能 | Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization. |
| 细胞定位 | Cell membrane, Golgi apparatus, Membrane |
| 预测分子量 | 71 kDa |
| 翻译后修饰 | Lipoprotein, Palmitate, Phosphoprotein |
检测图片 (2) Click the Picture to Zoom In
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ARG44289 anti-NSMase2 antibody ICC/IF image
Immunofluorescence: PC12 stained with ARG44289 anti-NSMase2 antibody.
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ARG44289 anti-NSMase2 antibody WB image
Western blot: Mouse brain stained with ARG44289 anti-NSMase2 antibody.
