ARG45657
anti-NSMCE4A antibody
anti-NSMCE4A antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NSMCE4A |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NSMCE4A |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human NSMCE4A. |
| 偶联标记 | Un-conjugated |
| 別名 | NSMCE4A; NSE4 Homolog A, SMC5-SMC6 Complex Component; C10orf86; NSE4A; Non-Structural Maintenance Of Chromosomes Element 4 Homolog A; NSE4 Homolog, SMC5-SMC6 Complex Component A; Non-SMC Element 4 Homolog A; BA500G22.3; FLJ20003; NS4EA; Non-SMC Element 4 Homolog A (S. Cerevisiae); Chromosome 10 Open Reading Frame 86 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 50 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9NXX6 Human Non-structural maintenance of chromosomes element 4 homolog A |
|---|---|
| 基因名称 | NSMCE4A |
| 全名 | NSE4 Homolog A, SMC5-SMC6 Complex Component |
| 背景介绍 | Involved in DNA damage response. Located in nuclear body. Part of Smc5-Smc6 complex. [provided by Alliance of Genome Resources, Feb 2025] |
| 生物功能 | Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Is involved in positive regulation of response to DNA damage stimulus. [UniProt] |
| 细胞定位 | Chromosome; Nucleus; Telomere. [UniProt] |
| 预测分子量 | 44 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
检测图片 (5) Click the Picture to Zoom In
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ARG45657 anti-NSMCE4A antibody ICC/IF image
Immunofluorescence: A549 stained with ARG45657 anti-NSMCE4A antibody at 5 μg/ml dilution.
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ARG45657 anti-NSMCE4A antibody WB image
Western blot: 293T and HepG2 stained with ARG45657 anti-NSMCE4A antibody at 0.5 μg/ml dilution.
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ARG45657 anti-NSMCE4A antibody FACS image
Flow Cytometry: JK stained with ARG45657 anti-NSMCE4A antibody at 1 µg/10^6 cells dilution.
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ARG45657 anti-NSMCE4A antibody WB image
Western blot: RH35 stained with ARG45657 anti-NSMCE4A antibody at 0.5 μg/ml dilution.
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ARG45657 anti-NSMCE4A antibody WB image
Western blot: Mouse ovary stained with ARG45657 anti-NSMCE4A antibody at 0.5 μg/ml dilution.
