概述

产品描述	Rabbit Polyclonal antibody recognizes NSD3
反应物种	Hu, Ms, Rat
应用	FACS, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	NSD3
抗原物种	Human
抗原	Synthetic peptide of Human NSD3.
偶联标记	Un-conjugated
別名	Wolf-Hirschhorn syndrome candidate 1-like protein 1; WHSC1-like 1 isoform 9 with methyltransferase activity to lysine; EC 2.1.1.43; WHSC1-like protein 1; Histone-lysine N-methyltransferase NSD3; NSD3; Protein whistle; Nuclear SET domain-containing protein 3; pp14328

应用说明

应用建议	应用 推荐稀释比 FACS 1:30 WB 1:1000 - 1:5000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	MCF7

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 234135 Mouse WHSC1L1 GeneID: 54904 Human WHSC1L1 Swiss-port # Q6P2L6 Mouse Histone-lysine N-methyltransferase NSD3 Swiss-port # Q9BZ95 Human Histone-lysine N-methyltransferase NSD3
基因名称	WHSC1L1
全名	Wolf-Hirschhorn syndrome candidate 1-like 1
背景介绍	This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described. [provided by RefSeq, May 2015]
生物功能	Histone methyltransferase. Preferentially methylates 'Lys-4' and 'Lys-27' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression. [UniProt]
细胞定位	Nucleus. Chromosome. [UniProt]
预测分子量	162 kDa

检测图片 (1) Click the Picture to Zoom In