ARG66443
anti-NRXN3 beta antibody
anti-NRXN3 beta antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NRXN3 beta |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NRXN3 beta |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide within aa. 30-110 of Human NRXN3 beta. |
| 偶联标记 | Un-conjugated |
| 別名 | C14orf60; Neurexin III-alpha; Neurexin-3; Neurexin-3-alpha |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | ~ 70 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol and 0.5% BSA |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NRXN3 |
| 全名 | neurexin 3 |
| 背景介绍 | This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder. [provided by RefSeq, Dec 2012] |
| 生物功能 | Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling. [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 181 kDa |
| 翻译后修饰 | Proccessed by alpha-secretase leading to the formation of an extracellular soluble protein as well as a C-terminal membrane-embedded fragment (CTF). Proteolysis of these CTFs by gamma-secretase releases intracellular domains (ICDs) and extracellular peptides. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG66443 anti-NRXN3 beta antibody WB image
Western blot: 293 cell lysate stained with ARG66443 anti-NRXN3 beta antibody. The lane on the right is blocked with the synthetic peptide.
