ARG44126
anti-NRDC antibody
anti-NRDC antibody for Flow cytometry,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal recognizes NRDC |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NRDC |
| 抗原物种 | Human |
| 抗原 | Human NRD1/NRDC recombinant protein (Position: K427-R967). |
| 偶联标记 | Un-conjugated |
| 別名 | NRDC; Nardilysin Convertase; HNRD1; HNRD2; NRD1; Nardilysin (N-Arginine Dibasic Convertase); N-Arginine Dibasic Convertase; NRD Convertase; EC 3.4.24.61; Nardilysin; EC 3.4.24; NRD-C |
应用说明
| 应用建议 |
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| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NRDC |
| 全名 | Nardilysin Convertase |
| 背景介绍 | This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene. |
| 生物功能 | Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs. Is a critical activator of BACE1- and ADAM17-mediated pro-neuregulin ectodomain shedding, involved in the positive regulation of axonal maturation and myelination. Required for proper functioning of 2-oxoglutarate dehydrogenase (OGDH). |
| 细胞定位 | Cell projection, Mitochondrion |
| 预测分子量 | 132 kDa |
| 翻译后修饰 | Phosphoprotein |
检测图片 (2) Click the Picture to Zoom In
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ARG44126 anti-NRDC antibody WB image
Western blot: K562 stained with ARG44126 anti-NRDC antibody at 0.5 μg/ml dilution.
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ARG44126 anti-NRDC antibody FACS image
Flow Cytometry: MCF-7 stained with ARG44126 anti-NRDC antibody at 1 µg/10^6 cells dilution.
