ARG44716
anti-NRBF2 antibody
anti-NRBF2 antibody for Immunoprecipitation,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes NRBF2 |
|---|---|
| 反应物种 | Hu |
| 应用 | IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2a |
| 靶点名称 | NRBF2 |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | Nuclear receptor-binding factor 2; COPR1; COPR2; Comodulator of PPAR and RXR; COPR; NRBF-2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NRBF2 |
| 全名 | nuclear receptor binding factor 2 |
| 生物功能 | May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro). Involved in starvation-induced autophagy probably by its association with PI3K complex I (PI3KC3-C1). However, effects has been described variably. Involved in the induction of starvation-induced autophagy. Stabilzes PI3KC3-C1 assembly and enhances ATG14-linked lipid kinase activity of PIK3C3 (By similarity). Proposed to negatively regulate basal and starvation-induced autophagy and to inhibit PIK3C3 activity by modulating interactions in PI3KC3-C1. May be involved in autophagosome biogenesis. May play a role in neural progenitor cell survival during differentiation (By similarity). [UniProt] |
| 细胞定位 | Nucleus. Cytoplasm. Cytoplasmic vesicle. Cytoplasmic vesicle, autophagosome. [UniProt] |
| 预测分子量 | 32 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG44716 anti-NRBF2 antibody WB image
Western blot: Jurkat, HepG, HeLa stained with ARG44716 anti-NRBF2 antibody at 1 µg/mL dilution.
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ARG44716 anti-NRBF2 antibody IP image
Immunoprecipitation: HepG2 lysate immunoprecipitated with 2.5 µg of ARG44716 anti-NRBF2 antibody.
