ARG55352
anti-NR0B1 / DAX1 antibody
anti-NR0B1 / DAX1 antibody for Western blot and Human
Developmental Biology antibody; Gene Regulation antibody; Neuroscience antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NR0B1 / DAX1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NR0B1 / DAX1 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 4-34 (N-terminus) of Human DAX1. |
| 偶联标记 | Un-conjugated |
| 別名 | AHC; GTD; SRXY2; DAX1; AHCH; DSS; NROB1; Nuclear receptor subfamily 0 group B member 1; HHG; Nuclear receptor DAX-1; DAX-1; AHX; DSS-AHC critical region on the X chromosome protein 1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | HeLa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P51843 Human Nuclear receptor subfamily 0 group B member 1 |
|---|---|
| 基因名称 | NR0B1 |
| 全名 | nuclear receptor subfamily 0, group B, member 1 |
| 背景介绍 | This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. [provided by RefSeq, Jul 2008] |
| 生物功能 | Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). [UniProt] |
| 细胞定位 | Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and nucleus. Homodimers exits in the cytoplasm and in the nucleus |
| 研究领域 | Developmental Biology antibody; Gene Regulation antibody; Neuroscience antibody |
| 预测分子量 | 52 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG55352 anti-NR0B1 / DAX1 antibody WB image
Western blot: 35 µg of HeLa cell lysate stained with ARG55352 anti-NR0B1 / DAX1 antibody.
