anti-NQO1 antibody

anti-NQO1 antibody for Western blot,ICC/IF,Immunoprecipitation,Flow cytometry and Human,Mouse,Rat

publication_link 参考文献1


产品描述 Rabbit Polyclonal antibody recognizes NQO1
反应物种 Hu, Ms, Rat
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 NQO1
抗原物种 Human
抗原 Synthetic peptide derived from Human NQO1.
偶联标记 Un-conjugated
別名 DTD; QR1; DHQU; DIA4; NMOR1; NMORI; NAD(P)H dehydrogenase [quinone] 1; EC; Azoreductase; DT-diaphorase; DTD; Menadione reductase; NAD(P)H:quinone oxidoreductase 1; Phylloquinone reductase; Quinone reductase 1; QR1


应用 推荐稀释比
ICC/IF1:50 - 1:200
WB1:1000 - 1:5000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 SH-SY5Y
实际分子量 ~ 32 kDa


形式 Liquid
纯化 Affinity purified.
缓冲液 PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.



GeneID: 1728 Human NQO1

GeneID: 18104 Mouse NQO1

GeneID: 24314 Rat NQO1

基因名称 NQO1
全名 NAD(P)H dehydrogenase, quinone 1
背景介绍 This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
生物功能 The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. [UniProt]
细胞定位 Cytoplasm. [UniProt]
产品亮点 Related Antibody Duos and Panels:
ARG30345 Keap1-Nrf2-ARE Antibody Panel
Related products:
NQO1 antibodies; NQO1 Duos / Panels; Anti-Rabbit IgG secondary antibodies;
Related news:
Keap1-Nrf2-ARE antibody panel is launched
预测分子量 31 kDa

检测图片 (2) Click the Picture to Zoom In

  • ARG43340 anti-NQO1 antibody ICC/IF image

    Immunofluorescence: MCF7 cells stained with ARG43340 anti-NQO1 antibody.

  • ARG43340 anti-NQO1 antibody WB image

    Western blot: SH-SY5Y cell lysate stained with ARG43340 anti-NQO1 antibody.


Identification of a novel immune-related gene signature for prognosis and the tumor microenvironment in patients with uveal melanoma combining single-cell and bulk sequencing data

WB / Human

Wanpeng Wang et al.
Front Immunol.,  (2023)