概述

产品描述	Sheep Polyclonal antibody recognizes NPY1R This antibody recognizes Human neuropeptide Y receptor 1. Neuropeptide Y receptors are a class of G-protein coupled receptors which are activated by the closely related peptide hormones neuropeptide Y, peptide YY and pancreatic polypeptide. These receptors are involved in control of a diverse set of behavioral processes including appetite, circadian rhythm, and anxiety.
反应物种	Hu, Rat
应用	ELISA, IHC-P, WB
宿主	Sheep
克隆	Polyclonal
同位型	IgG
靶点名称	NPY1R
抗原物种	Human
抗原	KLH-conjugated synthetic peptide around aa. 365 - 378 of Human NPY1R. (KQASPVAFKKINNN)
偶联标记	Un-conjugated
別名	NPYR; Neuropeptide Y receptor type 1; NPY1-R

应用说明

应用建议	应用 推荐稀释比 ELISA Assay-dependent IHC-P Assay-dependent WB 1:100 - 1:1000
应用说明	WB: This antibody detects a band of approximately 55 kDa in human brain. IHC-P: Antigen Retrieval: Boil tissue section in Sodium citrate buffer (pH 6.0) * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein G.
缓冲液	PBS and 0.09% Sodium azide.
抗菌剂	0.09% Sodium azide
浓度	5 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 4886 Human NPY1R Swiss-port # P25929 Human Neuropeptide Y receptor type 1
基因名称	NPY1R
全名	neuropeptide Y receptor Y1
背景介绍	This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. [provided by RefSeq, Aug 2013]
生物功能	Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY > [Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY > NPY (2-36) > [Ile-31, Gln-34] PP and PYY (3-36) > PP > NPY free acid. [UniProt]
预测分子量	44 kDa

检测图片 (1) Click the Picture to Zoom In