ARG64944
anti-NOX2 / gp91phox antibody
anti-NOX2 / gp91phox antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Cancer antibody; Immune System antibody; Metabolism antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes NOX2 / gp91phox |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Dog |
| 应用 | IHC-P |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NOX2 / gp91phox |
| 抗原物种 | Human |
| 抗原 | C-SYLNFARKRIKNP |
| 偶联标记 | Un-conjugated |
| 別名 | Neutrophil cytochrome b 91 kDa polypeptide; gp91-phox; NADPH oxidase 2; Heme-binding membrane glycoprotein gp91phox; 558; CGD91-phox; gp91-1; EC 1.-.-.-; Cytochrome b; GP91-1; IMD34; CGD; GP91-PHOX; AMCBX2; GP91PHOX; NOX2; Cytochrome b-245 heavy chain; p22 phagocyte B-cytochrome; p91-PHOX; Superoxide-generating NADPH oxidase heavy chain subunit; Cytochrome b558 subunit beta |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008] |
| 研究领域 | Cancer antibody; Immune System antibody; Metabolism antibody |
| 预测分子量 | 65 kDa |
| 翻译后修饰 | Glycosylated. Phosphorylated on Ser and Thr residues. |
检测图片 (1) Click the Picture to Zoom In
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ARG64944 anti-NOX2 / gp91phox antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human placenta tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64944 anti-NOX2 / gp91phox antibody at 3.8 µg/ml dilution followed by AP-staining.
