anti-NOX2 / gp91phox antibody

anti-NOX2 / gp91phox antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Cancer antibody; Immune System antibody; Metabolism antibody
publication_link 参考文献2


产品描述 Rabbit Polyclonal antibody recognizes NOX2 / gp91phox
反应物种 Hu, Ms, Rat
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 NOX2 / gp91phox
抗原物种 Human
抗原 Recombinant protein of Human CYBB (NP_000388.2)
偶联标记 Un-conjugated
別名 Neutrophil cytochrome b 91 kDa polypeptide; gp91-phox; NADPH oxidase 2; Heme-binding membrane glycoprotein gp91phox; 558; CGD91-phox; gp91-1; EC 1.-.-.-; Cytochrome b; GP91-1; IMD34; CGD; GP91-PHOX; AMCBX2; GP91PHOX; NOX2; Cytochrome b-245 heavy chain; p22 phagocyte B-cytochrome; p91-PHOX; Superoxide-generating NADPH oxidase heavy chain subunit; Cytochrome b558 subunit beta


应用 推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 THP-1


形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.



GeneID: 13058 Mouse CYBB

GeneID: 1536 Human CYBB

Swiss-port # P04839 Human Cytochrome b-245 heavy chain

Swiss-port # Q61093 Mouse Cytochrome b-245 heavy chain

基因名称 CYBB
全名 cytochrome b-245, beta polypeptide
背景介绍 Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]
生物功能 Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc. [UniProt]
研究领域 Cancer antibody; Immune System antibody; Metabolism antibody
预测分子量 65 kDa
翻译后修饰 Glycosylated.
Phosphorylated on Ser and Thr residues.

检测图片 (3) Click the Picture to Zoom In

  • ARG55310 anti-NOX2 / gp91phox antibody ICC/IF image

    Immunofluorescence: A431 cells stained with ARG55310 anti-NOX2 / gp91phox antibody at 1:100 dilution.

  • ARG55310 anti-NOX2 / gp91phox antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse brain stained with ARG55310 anti-NOX2 / gp91phox antibody at 1:100 dilution.

  • ARG55310 anti-NOX2 / gp91phox antibody WB image

    Western blot: THP-1 cell lysate stained with ARG55310 anti-NOX2 / gp91phox antibody.


Pterostilbene Interferes With Lipopolysaccharide-Induced Myocardial Injury Through Oxidative Stress and Inflammasome Pathways

WB / Mouse

Lei Zhang et al.
Front Physiol .,  (2022)




Neohesperidin Protects Angiotensin II-Induced Hypertension and Vascular Remodeling.

WB / Mouse

Zhang J et al.
Frontiers in Pharmacology,  (2022)