anti-NOX1 antibody

anti-NOX1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

publication_link 参考文献1


产品描述 Rabbit Polyclonal antibody recognizes NOX1
反应物种 Hu
预测物种 Hm
应用 IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 NOX1
抗原物种 Human
抗原 Synthetic peptide corresponding to aa. 354-374 of Human NOX1. (HIRAAGDWTENLIRAFEQQYS)
偶联标记 Un-conjugated
別名 NOH1; GP91-2; NOX-1; NADPH oxidase 1; MOX-1; Mitogenic oxidase 1; MOX1; EC 1.-.-.-; NOH-1; NADH/NADPH mitogenic oxidase subunit P65-MOX


应用 推荐稀释比
IHC-P0.5 - 1 µg/ml
WB0.1 - 0.5 µg/ml
应用说明 IHC-P: Antigen Retrieval: Heat mediation was recommended.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 0.2% Na2HPO4, 0.9% NaCl, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA.
抗菌剂 0.05% Thimerosal and 0.05% Sodium azide
稳定剂 5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.



GeneID: 27035 Human NOX1

Swiss-port # Q9Y5S8 Human NADPH oxidase 1

基因名称 NOX1
全名 NADPH oxidase 1
背景介绍 This gene encodes a member of the NADPH oxidase family of enzymes responsible for the catalytic one-electron transfer of oxygen to generate superoxide or hydrogen peroxide. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]
生物功能 NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain. [UniProt]
细胞定位 Cell projection, invadopodium membrane; Multi-pass membrane protein. Cell membrane. [UniProt]
预测分子量 65 kDa

检测图片 (2) Click the Picture to Zoom In

  • ARG59887 anti-NOX1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human lung cancer tissue stained with ARG59887 anti-NOX1 antibody.

  • ARG59887 anti-NOX1 antibody WB image

    Western blot: 40 µg of HeLa and MCF7 whole cell lysates stained with ARG59887 anti-NOX1 antibody at 0.5 µg/ml dilution.


PROX1 induction by autolysosomal activity stabilizes persister-like state of colon cancer via feedback repression of the NOX1-mTORC1 pathway

WB / Human

Hirokazu Ohata et al.
Cell Reports,  (2023)