ARG46336
anti-NOSTRIN antibody
anti-NOSTRIN antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NOSTRIN |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NOSTRIN |
| 抗原物种 | Human |
| 抗原 | A 17 amino acid synthetic peptide within the last 50 amino acids of human NOSTRIN. |
| 偶联标记 | Un-conjugated |
| 別名 | NOSTRIN; nitric oxide synthase trafficking; Nitric oxide synthase traffic inducer; eNOS-trafficking inducer; Nitric oxide synthase trafficker; BM247 homolog; DaIP2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 68 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -386°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NOSTRIN |
| 全名 | nitric oxide synthase trafficking |
| 背景介绍 | Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.[supplied by OMIM, Apr 2004] |
| 生物功能 | Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane. [UniProt] |
| 细胞定位 | Cytoplasm; Nucleus; Cytoskeleton; Cell membrane ; Cytoplasmic vesicle; Cytoplasmic vesicle. [UniProt] |
| 预测分子量 | 47, 53, 56, 62 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
