ARG40542
anti-NOMO1 + NOMO2 + NOMO3 antibody
anti-NOMO1 + NOMO2 + NOMO3 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NOMO1 + NOMO2 + NOMO3 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NOMO1 + NOMO2 + NOMO3 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 873-1222 of Human NOMO2 (NP_001004060.1). |
| 偶联标记 | Un-conjugated |
| 別名 | Nodal modulator 2; PM5; pM5 protein 2; Nomo |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | BxPC-3 | ||||
| 实际分子量 | ~ 140 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NOMO2 |
| 全名 | NODAL modulator 2 |
| 背景介绍 | This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE). Two transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| 生物功能 | May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning, via its interaction with NCLN. [UniProt] |
| 细胞定位 | Endoplasmic reticulum membrane; Single-pass membrane protein. [UniProt] |
| 预测分子量 | 139 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG40542 anti-NOMO1 + NOMO2 + NOMO3 antibody WB image
Western blot: 25 µg of BxPC-3 cell lysate stained with ARG40542 anti-NOMO1 + NOMO2 + NOMO3 antibody at 1:1000 dilution.
