ARG43160
anti-NNT antibody
anti-NNT antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NNT |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NNT |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 881-1086 of Human NNT (NP_036475.3). |
| 偶联标记 | Un-conjugated |
| 別名 | GCCD4; NAD(P) transhydrogenase, mitochondrial; EC 1.6.1.2; Nicotinamide nucleotide transhydrogenase; Pyridine nucleotide transhydrogenase |
应用说明
| 预测反应性说明 | Human | ||||
|---|---|---|---|---|---|
| 应用建议 |
|
||||
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse liver | ||||
| 实际分子量 | ~ 128 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q13423 Human NAD(P) transhydrogenase, mitochondrial |
|---|---|
| 基因名称 | NNT |
| 全名 | nicotinamide nucleotide transhydrogenase |
| 背景介绍 | This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. [provided by RefSeq, Sep 2016] |
| 生物功能 | The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity). May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland (PubMed:22634753). [UniProt] |
| 细胞定位 | Mitochondrion inner membrane; Multi-pass membrane protein; Matrix side. [UniProt] |
| 预测分子量 | 114 kDa |
检测图片 (1) Click the Picture to Zoom In
-
ARG43160 anti-NNT antibody WB image
Western blot: 25 µg of Mouse liver lysate stained with ARG43160 anti-NNT antibody at 1:3000 dilution.
