ARG45708
anti-NMI / n Myc Interactor antibody
anti-NMI / n Myc Interactor antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NMI / n Myc Interactor |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NMI / n Myc Interactor |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human NMI / n Myc Interactor . |
| 偶联标记 | Un-conjugated |
| 別名 | N-myc (and STAT) interactor; N-myc and STAT interactor; N-myc-interactor; Nmi |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 35 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NMI |
| 全名 | N-myc (and STAT) interactor |
| 背景介绍 | NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. [provided by RefSeq, Jul 2008] |
| 生物功能 | May be involved in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors. Augments cytokine-mediated STAT transcription. Enhances CBP/p300 coactivator protein recruitment to STAT1 and STAT5. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 35 kDa |
| 翻译后修饰 | Isopeptide bond; Phosphoprotein; Ubl conjugation. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG45708 anti-NMI / n Myc Interactor antibody IHC-P image
Immunohistochemistry: Human colon cancer stained with ARG45708 anti-NMI / n Myc Interactor antibody at 2 μg/ml dilution.
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ARG45708 anti-NMI / n Myc Interactor antibody ICC/IF image
Immunofluorescence: A431 stained with ARG45708 anti-NMI / n Myc Interactor antibody at 5 μg/ml dilution.
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ARG45708 anti-NMI / n Myc Interactor antibody WB image
Western blot: Human placenta and K562 stained with ARG45708 anti-NMI / n Myc Interactor antibody at 0.5 μg/ml dilution.
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ARG45708 anti-NMI / n Myc Interactor antibody FACS image
Flow Cytometry: U937 stained with ARG45708 anti-NMI / n Myc Interactor antibody at 1 µg/10^6 cells dilution.
