anti-NMDAR2A antibody, N-terminal

anti-NMDAR2A antibody, N-terminal for ICC/IF,IHC-Frozen sections,Western blot and Mouse,Rat

Neuroscience antibody; Postsynaptic Receptor antibody
publication_link 参考文献1


产品描述 Rabbit Polyclonal antibody recognizes NMDAR2A
反应物种 Ms, Rat
预测物种 Bov, Dog
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 NMDAR2A
抗原物种 Rat
抗原 Synthetic peptide corresponding to amino acid residues from the N-terminal region of the NR2A subunit conjugated to KLH
偶联标记 Un-conjugated
別名 FESD; NR2A; GluN2A; Glutamate receptor ionotropic, NMDA 2A; N-methyl D-aspartate receptor subtype 2A; EPND; Glutamate [NMDA] receptor subunit epsilon-1; NMDAR2A; LKS; hNR2A


应用 推荐稀释比
ICC/IF1:200 - 1:500
IHC-Fr1:200 - 1:500
应用说明 Specific for the ~180k NR2A subunit of the NMDA receptor.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


形式 Liquid
纯化 Affinity Purified
缓冲液 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol
稳定剂 0.1 mg/ml BSA, 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.



GeneID: 14811 Mouse GRIN2A

GeneID: 24409 Rat GRIN2A

Swiss-port # P35436 Mouse Glutamate receptor ionotropic, NMDA 2A

Swiss-port # Q00959 Rat Glutamate receptor ionotropic, NMDA 2A

基因名称 GRIN2A
全名 glutamate receptor, ionotropic, N-methyl D-aspartate 2A
背景介绍 The ion channels activated by glutamate are typically divided into two classes. Glutamate receptors that are activated by kainate and α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death (Grosshans et al., 2002; Wenthold et al., 2003; Carroll and Zukin, 2002). The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS (Lovinger et al., 1989; Alvestad et al., 2003; Snell et al., 1996). The NMDAR is also potentiated by protein phosphorylation (Lu et al., 1999). The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits.
研究领域 Neuroscience antibody; Postsynaptic Receptor antibody
预测分子量 165 kDa

检测图片 (1) Click the Picture to Zoom In

  • ARG52360 anti-NMDAR2A antibody, N-terminal WB image

    Western Blot: 10 μg of rat hippocampal lysate showing specific immunolabeling of the ~ 180k NR2A subunit stained with NMDAR2A antibody (ARG52360)


Involvement of NMDAR/PSD-95/nNOS-NO-cGMP pathway in embryonic exposure to BPA induced learning and memory dysfunction of rats.

WB / Rat

Yu Haiyang et al.
Environ Pollut.,  (2020)