ARG45924
anti-NKG7 antibody
anti-NKG7 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NKG7 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NKG7 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to C-terminal region of human NKG7. |
| 偶联标记 | Un-conjugated |
| 別名 | Natural Killer Cell Granule Protein 7; NKG7; GIG1; Protein NKG7; G-CSF-induced gene 1 protein; GIG-1 protein; Granule membrane protein of 17 kDa; GMP-17; Natural killer cell protein 7; p15-TIA-1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 18 - 25 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NKG7 |
| 全名 | Natural Killer Cell Granule Protein 7 |
| 背景介绍 | Involved in defense response to protozoan. Located in cytolytic granule membrane and plasma membrane. [provided by Alliance of Genome Resources, Feb 2025] |
| 生物功能 | Regulates cytotoxic granule exocytosis in effector lymphocytes, thus acting as a critical mediator of inflammation in a broad range of infectious and non-infectious diseases (By similarity). Essential for cytotoxic degranulation of natural killer (NK) cells and CD8+ T-cells and for the activation of CD4+ T-cells following infection (By similarity). Plays a critical role in CD8+ T-cell and NK cell-mediated cytolysis of target cells and contributes to the cytolytic activity via the perforin/granzyme pathway by enhancing exocytosis of LAMP1-carrying lytic granules (By similarity). Contributes to NK cell-mediated control of cancer metastasis (By similarity). [UniProt] |
| 细胞定位 | Cell membrane; Lysosome. [UniProt] |
| 预测分子量 | 18 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG45924 anti-NKG7 antibody IHC-P image
Immunohistochemistry: Human stomach cancer stained with ARG45924 anti-NKG7 antibody at 2 μg/ml dilution.
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ARG45924 anti-NKG7 antibody WB image
Western blot: HEL stained with ARG45924 anti-NKG7 antibody at 0.5 μg/ml dilution.
