ARG56331

anti-NFS1 antibody

anti-NFS1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes NFS1
反应物种 Hu, Ms, Rat
应用 ICC/IF, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 NFS1
抗原物种 Human
抗原 Recombinant protein of Human NFS1
偶联标记 Un-conjugated
別名 HUSSY-08; NIFS; EC 2.8.1.7; IscS; Cysteine desulfurase, mitochondrial

应用说明

应用建议
应用 推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 Rat liver

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 18041 Mouse NFS1

GeneID: 9054 Human NFS1

Swiss-port # Q9Y697 Human Cysteine desulfurase, mitochondrial

Swiss-port # Q9Z1J3 Mouse Cysteine desulfurase, mitochondrial

基因名称 NFS1
全名 NFS1 cysteine desulfurase
背景介绍 Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010]
生物功能 Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters. May be involved in the biosynthesis of molybdenum cofactor. [UniProt]
预测分子量 50 kDa

检测图片 (3) Click the Picture to Zoom In

  • ARG56331 anti-NFS1 antibody ICC/IF image

    Immunofluorescence: HeLa cells stained with ARG56331 anti-NFS1 antibody.

  • ARG56331 anti-NFS1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human liver cancer stained with ARG56331 anti-NFS1 antibody at 1:100 dilution.

  • ARG56331 anti-NFS1 antibody WB image

    Western blot: Rat liver lysate stained with ARG56331 anti-NFS1 antibody.