ARG63982

anti-NET1 / ARHGEF8 antibody

anti-NET1 / ARHGEF8 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human

Cancer antibody; Gene Regulation antibody; Signaling Transduction antibody

概述

产品描述 Goat Polyclonal antibody recognizes NET1 / ARHGEF8
反应物种 Hu
预测物种 Ms, Rat, Dog
应用 IHC-P
特异性 This antibody is expected to recognize both reported isoforms (NP_001040625.1 and NP_005854.2).
宿主 Goat
克隆 Polyclonal
同位型 IgG
靶点名称 NET1 / ARHGEF8
抗原物种 Human
抗原 C-DKLEYLDEKQRDPR
偶联标记 Un-conjugated
別名 Rho guanine nucleotide exchange factor 8; NET1A; Proto-oncogene p65 Net1; Neuroepithelial cell-transforming gene 1 protein; ARHGEF8

应用说明

应用建议
应用 推荐稀释比
IHC-P2.5 µg/ml
应用说明 IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purified from goat serum by antigen affinity chromatography.
缓冲液 Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 0.5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 10276 Human NET1

Swiss-port # Q7Z628 Human Neuroepithelial cell-transforming gene 1 protein

背景介绍 This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
研究领域 Cancer antibody; Gene Regulation antibody; Signaling Transduction antibody
预测分子量 68 kDa

检测图片 (1) Click the Picture to Zoom In

  • ARG63982 anti-NET1 / ARHGEF8 antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Breast. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63982 anti-NET1 / ARHGEF8 antibody at 2.5 µg/ml dilution followed by AP-staining.