ARG65578
anti-NDUFS8 antibody
anti-NDUFS8 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Cancer antibody; Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NDUFS8 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NDUFS8 |
| 抗原物种 | Human |
| 抗原 | Fusion protein of human NDUFS8 |
| 偶联标记 | Un-conjugated |
| 別名 | EC 1.6.5.3; TYKY; NADH-ubiquinone oxidoreductase 23 kDa subunit; CI-23k; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; CI23KD; Complex I-23kD; EC 1.6.99.3; CI-23kD; TYKY subunit |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Jurkat cell, mouse heart and brain tissue |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified by antigen-affinity chromatography. |
| 缓冲液 | 1XPBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 40% Glycerol |
| 浓度 | 0.9 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O00217 Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial Swiss-port # Q8K3J1 Mouse NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial |
|---|---|
| 基因名称 | NDUFS8 |
| 全名 | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) |
| 背景介绍 | This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome. |
| 生物功能 | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). May donate electrons to ubiquinone. [UniProt] |
| 产品亮点 | Related products: NDUFS8 antibodies; Anti-Rabbit IgG secondary antibodies; Related poster download: The Structure & Functions of Mitochondria.pdf |
| 研究领域 | Cancer antibody; Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody |
| 预测分子量 | 24 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG65578 anti-NDUFS8 antibody WB image
Western blot: 40 μg of 1) Jurkat, 2) Mouse heart, and 3) Mouse brain lysates stained with ARG65578 anti-NDUFS8 antibody at 1:250 dilution. Exposure time: 20 seconds.
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ARG65578 anti-NDUFS8 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human thyroid cancer tissue stained with ARG65578 anti-NDUFS8 antibody (left) at 1:20 dilution, or the same antibody preincubated with fusion protein (right). (Original magnification: ×200).
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ARG65578 anti-NDUFS8 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human thyroid cancer tissue stained with ARG65578 anti-NDUFS8 antibody (left) at 1:20 dilution, or the same antibody preincubated with fusion protein (right). (Original magnification: ×200).
