ARG10666
anti-NDUFA1 antibody
anti-NDUFA1 antibody for ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NDUFA1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-Fr, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NDUFA1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the C-terminus of Human NDUFA1. (ISGVDRYYVSKGLENID) |
| 偶联标记 | Un-conjugated |
| 別名 | MWFE; ZNF183; NADH-ubiquinone oxidoreductase MWFE subunit; CI-MWFE; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1; Complex I-MWFE |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.025% Sodium azide and 2.5% BSA. |
| 抗菌剂 | 0.025% Sodium azide |
| 稳定剂 | 2.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O15239 Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 Swiss-port # O35683 Mouse NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 |
|---|---|
| 基因名称 | NDUFA1 |
| 全名 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa |
| 背景介绍 | The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008] |
| 生物功能 | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [UniProt] |
| 预测分子量 | 8 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG10666 anti-NDUFA1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat heart tissue stained with ARG10666 anti-NDUFA1 antibody.
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ARG10666 anti-NDUFA1 antibody WB image
Western blot: 1) Rat heart, 2) Rat liver, 3) Rat kidney, 4) Rat brain, and 5) Human HT1080 cell lysates stained with ARG10666 anti-NDUFA1 antibody.
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ARG10666 anti-NDUFA1 antibody IHC-Fr image
Immunohistochemistry: Frozen section of Rat heart tissue stained with ARG10666 anti-NDUFA1 antibody.
