ARG46322

anti-NDST2 antibody

anti-NDST2 antibody for Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes NDST2
反应物种 Hu, Ms, Rat
应用 WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 NDST2
抗原物种 Human
抗原 A 16 amino acid synthetic peptide within aa. 20 - 70 of human NDST2.
偶联标记 Un-conjugated
別名 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2; NDST2; NST2; HSST2; N-heparan sulfate sulfotransferase 2; NDST-2

应用说明

应用建议
应用 推荐稀释比
WBAssay-dependent
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量 101 kDa

属性

形式 Liquid
纯化 Affinity chromatography purified
缓冲液 PBS and 0.02% Sodium azide.
抗菌剂 0.02% Sodium azide
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -372°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 17423 Mouse NDST2

GeneID: 8509 Human NDST2

Swiss-port # P52849 Human Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2

Swiss-port # P52850 Mouse Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2

基因名称 NDST2
全名 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
背景介绍 This gene encodes a member of the N-deacetylase/N-sulfotransferase subfamily of the sulfotransferase 1 proteins. The encoded enzyme has dual functions in processing glucosamine and heparin polymers, including N-deacetylation and N-sulfation. The encoded protein may be localized to the Golgi. [provided by RefSeq, Feb 2009]
生物功能 Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Required for the exosomal release of SDCBP, CD63 and syndecan. [UniProt]
细胞定位 Golgi apparatus. [UniProt]
预测分子量 97 kDa
翻译后修饰 Disulfide bond; Glycoprotein. [UniProt]