ARG46321
anti-NDST1 antibody
anti-NDST1 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NDST1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NDST1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide near the amino terminus of human NDST1. |
| 偶联标记 | Un-conjugated |
| 別名 | N-deacetylase and N-sulfotransferase 1; NDST1; HSST; NST1; MRT46 |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | 97 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -371°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | NDST1 |
|---|---|
| 全名 | N-deacetylase and N-sulfotransferase 1 |
| 背景介绍 | Enables N-acetylglucosamine deacetylase activity; heparan sulfate N-deacetylase activity; and heparan sulfate N-sulfotransferase activity. Involved in heparan sulfate proteoglycan biosynthetic process. Acts upstream of or within several processes, including circulatory system development; embryonic cranial skeleton morphogenesis; and positive regulation of signal transduction. Is active in Golgi apparatus. Is expressed in several structures, including exocrine system; future brain; integumental system; nervous system; and respiratory system. Used to study DiGeorge syndrome; congenital diaphragmatic hernia; and newborn respiratory distress syndrome. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 46. Orthologous to human NDST1 (N-deacetylase and N-sulfotransferase 1). [provided by Alliance of Genome Resources, Jul 2025] |
| 生物功能 | [Isoform 1]: Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. [UniProt] |
| 细胞定位 | Golgi apparatus. [UniProt] |
| 预测分子量 | 97 kDa |
| 翻译后修饰 | Disulfide bond; Glycoprotein. [UniProt] |
