ARG59486
anti-NDRG2 antibody
anti-NDRG2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Goat Polyclonal antibody recognizes NDRG2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 预测物种 | Dog |
| 应用 | IHC-P, WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NDRG2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide near the N-terminus of Human NDRG2. (KEAELAARILLDQGQ-C, NP_963293.1) |
| 偶联标记 | Un-conjugated |
| 別名 | Protein Syld709613; N-myc downstream-regulated gene 2 protein; SYLD; Protein NDRG2 |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 实际分子量 | ~ 45 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NDRG2 |
| 全名 | NDRG family member 2 |
| 背景介绍 | This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008] |
| 生物功能 | Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation. [UniProt] |
| 细胞定位 | Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Note=In neurons, seems to concentrate at axonal growth cone. Perinuclear in neurons (By similarity). [UniProt] |
| 预测分子量 | 41 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG59486 anti-NDRG2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human adrenal gland stained with ARG59486 anti-NDRG2 antibody at 3.75 µg/ml dilution. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
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ARG59486 anti-NDRG2 antibody WB image
Western blot: 35 µg of Human temporal cortex lysate (in RIPA buffer) stained with ARG59486 anti-NDRG2 antibody at 0.1 µg/ml dilution and incubated at RT for 1 hour.
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ARG59486 anti-NDRG2 antibody WB image
Western blot: 35 µg of Mouse brain and Rat brain lysates (in RIPA buffer) stained with ARG59486 anti-NDRG2 antibody at 0.3 µg/ml dilution and incubated at RT for 1 hour.
