ARG45411
anti-NDFIP2 antibody [10D6D7]
anti-NDFIP2 antibody [10D6D7] for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [10D6D7] recognizes NDFIP2 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 10D6D7 |
| 同位型 | IgG2b |
| 靶点名称 | NDFIP2 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human NDFIP2. |
| 偶联标记 | Un-conjugated |
| 別名 | NDFIP2; Nedd4 Family Interacting Protein 2; KIAA1165; N4wbp5a; Putative MAPK-Activating Protein PM04/PM05/PM06/PM07; Putative NF-Kappa-B-Activating Protein 413; NEDD4 Family-Interacting Protein 2; NEDD4 WW Domain-Binding Protein 5A; MAPK-Activating Protein PM04 PM05 PM06 PM07; NF-Kappa-B-Activating Protein 413; N4WBP5A |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 39 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9NV92 Human NEDD4 family-interacting protein 2 |
|---|---|
| 基因名称 | NDFIP2 |
| 全名 | Nedd4 Family Interacting Protein 2 |
| 背景介绍 | Enables WW domain binding activity. Involved in negative regulation of gene expression; negative regulation of transport; and positive regulation of protein ubiquitination. Located in several cellular components, including Golgi apparatus; mitochondrion; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Nov 2024] |
| 生物功能 | Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, may control many cellular processes. Recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. Negatively regulates KCNH2 potassium channel activity by decreasing its cell-surface expression and interfering with channel maturation through recruitment of NEDD4L to the Golgi apparatus and multivesicular body where it mediates KCNH2 degradation. [UniProt] |
| 细胞定位 | Endosome; Golgi apparatus; Membrane. [UniProt] |
| 预测分子量 | 36 kDa |
| 翻译后修饰 | Phosphoprotein; Ubl conjugation. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG45411 anti-NDFIP2 antibody [10D6D7] IHC-P image
Immunohistochemistry: Human placenta stained with ARG45411 anti-NDFIP2 antibody [10D6D7] at 2 μg/ml dilution.
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ARG45411 anti-NDFIP2 antibody [10D6D7] ICC/IF image
Immunofluorescence: A431 stained with ARG45411 anti-NDFIP2 antibody [10D6D7] at 5 μg/ml dilution.
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ARG45411 anti-NDFIP2 antibody [10D6D7] WB image
Western blot: A549 stained with ARG45411 anti-NDFIP2 antibody [10D6D7] at 0.5 μg/ml dilution.
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ARG45411 anti-NDFIP2 antibody [10D6D7] FACS image
Flow Cytometry: JK stained with ARG45411 anti-NDFIP2 antibody [10D6D7] at 1 µg/10^6 cells dilution.
