ARG22546
anti-NCR1 antibody [AKS1]
anti-NCR1 antibody [AKS1] for Flow cytometry,ICC/IF,Western blot and Bovine
概述
| 产品描述 | Mouse Monoclonal antibody [AKS1] recognizes NCR1 This antibody recognizes bovine CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1. CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor. CD335 is expressed by human natural killer cells (Sivori et al. 1997). The bovine homologue is expressed on bovine NK cells (Storset et al. 2004) and no expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes.Clone AKS1 is reported to activate lysis of FcgammaR-expressing cell line P815, by IL-2 activated NKp46+ cells (Storset et al. 2004). |
|---|---|
| 反应物种 | Bov |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | AKS1 |
| 同位型 | IgG1 |
| 靶点名称 | NCR1 |
| 抗原物种 | Bovine |
| 抗原 | Fusion protein consisting of the extracellular region of bovine CD335. |
| 偶联标记 | Un-conjugated |
| 別名 | CD antigen CD335; Natural killer cell p46-related protein; Lymphocyte antigen 94 homolog; Natural cytotoxicity triggering receptor 1; hNKp46; NKP46; NKp46; NK cell-activating receptor; LY94; CD335; NK-p46 |
应用说明
| 应用建议 |
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| 应用说明 | FACS: Use 10ul of the suggested working dilution to label 10^6 cells in 100ul. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS and 0.09% Sodium azide |
| 抗菌剂 | 0.09% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q863H2 Bovine Natural cytotoxicity triggering receptor 1 |
|---|---|
| 基因名称 | NCR1 |
| 全名 | natural cytotoxicity triggering receptor 1 |
| 生物功能 | Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. [UniProt] |
| 预测分子量 | 34 kDa |
| 翻译后修饰 | N-glycosylated. O-glycosylated. |
检测图片 (1) Click the Picture to Zoom In
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ARG22546 anti-NCR1 antibody [AKS1] FACS image
Flow Cytometry: Bovine peripheral blood lymphocytes stained with ARG22546 anti-NCR1 antibody [AKS1] followed by Goat anti Mouse IgG (H/L) (FITC). A small positive peak representing NK cells can be identified.
