ARG55464

anti-NCF1 / p47phox antibody

anti-NCF1 / p47phox antibody for ICC/IF,Immunoprecipitation,Western blot and Human,Mouse,Rat

Cancer antibody; Metabolism antibody; Signaling Transduction antibody

概述

产品描述 Rabbit Polyclonal antibody recognizes NCF1 / p47phox
反应物种 Hu, Ms, Rat
应用 ICC/IF, IP, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 NCF1 / p47phox
抗原物种 Human
抗原 Recombinant protein of Human NCF1 (NP_000256.4)
偶联标记 Un-conjugated
別名 Nox organizer 2; SH3PXD1A; NCF-47K; 47 kDa autosomal chronic granulomatous disease protein; NOXO2; Nox-organizing protein 2; 47 kDa neutrophil oxidase factor; Neutrophil cytosol factor 1; SH3 and PX domain-containing protein 1A; p47phox; NCF1A; Neutrophil NADPH oxidase factor 1; p47-phox; NCF-1

应用说明

预测反应性说明 Rat
应用建议
应用 推荐稀释比
ICC/IF1:50 - 1:200
IPAssay-dependent
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 Mouse lung

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 17969 Mouse NCF1

GeneID: 653361 Human NCF1

Swiss-port # P14598 Human Neutrophil cytosol factor 1

Swiss-port # Q09014 Mouse Neutrophil cytosol factor 1

基因名称 NCF1
全名 neutrophil cytosolic factor 1
背景介绍 The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. [provided by RefSeq, Jul 2008]
生物功能 NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). [UniProt]
研究领域 Cancer antibody; Metabolism antibody; Signaling Transduction antibody
预测分子量 45 kDa
翻译后修饰 Phosphorylated by PRKCD; phosphorylation induces activation of NCF1 and NADPH oxidase activity.

检测图片 (1) Click the Picture to Zoom In

  • ARG55464 anti-NCF1 / p47phox antibody WB image

    Western blot: Mouse lung lysate stained with ARG55464 anti-NCF1 / p47phox antibody.