ARG65701
anti-NBR1 antibody
anti-NBR1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Cell Biology and Cellular Response antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NBR1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NBR1 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human NBR1. |
| 偶联标记 | Un-conjugated |
| 別名 | Protein 1A1-3B; Neighbor of BRCA1 gene 1 protein; Membrane component chromosome 17 surface marker 2; Cell migration-inducing gene 19 protein; M17S2; IAI3B; Next to BRCA1 gene 1 protein; MIG19; 1A1-3B |
应用说明
| 预测反应性说明 | Monkey, Rat | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用建议 |
|
||||||||
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | HeLa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NBR1 |
| 全名 | neighbor of BRCA1 gene 1 |
| 背景介绍 | The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
| 生物功能 | Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets. [UniProt] |
| 研究领域 | Cell Biology and Cellular Response antibody |
| 预测分子量 | 107 kDa |
检测图片 (6) Click the Picture to Zoom In
-
ARG65701 anti-NBR1 antibody IHC-P image
Immunohistochemistry: Human colon stained with ARG65701 anti-NBR1 antibody at 1:100 dilution.
-
ARG65701 anti-NBR1 antibody ICC/IF image
Immunofluorescence: PC-12 stained with ARG65701 anti-NBR1 antibody at 1:50 dilution.
-
ARG65701 anti-NBR1 antibody WB image
Western blot: HeLa and 293F stained with ARG65701 anti-NBR1 antibody at 1:400 dilution.
-
ARG65701 anti-NBR1 antibody IHC-P image
Immunohistochemistry: Rat testis stained with ARG65701 anti-NBR1 antibody at 1:100 dilution.
-
ARG65701 anti-NBR1 antibody IHC-P image
Immunohistochemistry: Mouse heart stained with ARG65701 anti-NBR1 antibody at 1:100 dilution.
-
ARG65701 anti-NBR1 antibody ICC/IF image
Immunofluorescence: NIH/3T3 stained with ARG65701 anti-NBR1 antibody at 1:50 dilution.
