ARG44073
anti-NARF antibody
anti-NARF antibody for Flow cytometry,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal recognizes NARF |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NARF |
| 抗原物种 | Human |
| 抗原 | Human NARF recombinant protein (Position: H41-Q353). |
| 偶联标记 | Un-conjugated |
| 別名 | NARF; Nuclear Prelamin A Recognition Factor; IOP2; Iron-Only Hydrogenase-Like Protein 2; DKFZp434G0420; FLJ10067; Prenyl-Dependent Prelamin A Binding Protein |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NARF |
| 全名 | Nuclear Prelamin A Recognition Factor |
| 背景介绍 | Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. The encoded protein is located in the nucleus, where it partially colocalizes with the nuclear lamina. It shares limited sequence similarity with iron-only bacterial hydrogenases. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene, including one with a novel exon that is generated by RNA editing. |
| 细胞定位 | Nucleus |
| 预测分子量 | 51 kDa |
| 翻译后修饰 | Phosphoprotein |
检测图片 (4) Click the Picture to Zoom In
-
ARG44073 anti-NARF antibody WB image
Western blot: K562 stained with ARG44073 anti-NARF antibody at 0.5 μg/mL dilution.
-
ARG44073 anti-NARF antibody FACS image
Flow Cytometry: 293T stained with ARG44073 anti-NARF antibody at 1 μg/1x10^6 cells dilution.
-
ARG44073 anti-NARF antibody WB image
Western blot: Rat brain stained with ARG44073 anti-NARF antibody at 0.5 μg/mL dilution.
-
ARG44073 anti-NARF antibody WB image
Western blot: Mouse brain stained with ARG44073 anti-NARF antibody at 0.5 μg/mL dilution.
