ARG45684

anti-NANS antibody

anti-NANS antibody for ICC/IF,Western blot and Human,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes NANS
反应物种 Hu, Rat
应用 ICC/IF, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 NANS
抗原物种 Human
抗原 Recombinant protein containing to human NANS.
偶联标记 Un-conjugated
別名 NANS; N-Acetylneuraminate Synthase; SAS; Sialic Acid Synthase; 3-Deoxy-D-Glycero-D-Galacto-Nononate 9-Phosphate Synthase; N-Acetylneuraminic Acid Phosphate Synthase; N-Acetylneuraminate-9-Phosphate Synthase; N-Acetylneuraminic Acid Synthase; Sialic Acid Phosphate Synthase; Epididymis Secretory Protein Li 100; EC 2.5.1.132; EC 2.5.1.57; HEL-S-100; SEMDCG; SEMDG

应用说明

应用建议
应用 推荐稀释比
ICC/IF5 μg/ml
WB0.25-0.5 μg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量 38 kDa

属性

形式 Liquid
纯化 Affinity purified
缓冲液 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
稳定剂 4% Trehalose
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 54187 Human NANS

Swiss-port # Q9NR45 Human Sialic acid synthase

基因名称 NANS
全名 N-Acetylneuraminate Synthase
背景介绍 This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant. [provided by RefSeq, Jul 2008]
生物功能 Catalyzes the condensation of phosphoenolpyruvate (PEP) and N-acetylmannosamine 6-phosphate (ManNAc-6-P) to synthesize N-acetylneuraminate-9-phosphate (Neu5Ac-9-P). [UniProt]
细胞定位 Cytoplasm; Cytosol. [UniProt]
预测分子量 40 kDa
翻译后修饰 Acetylation; Phosphoprotein. [UniProt]

检测图片 (3) Click the Picture to Zoom In

  • ARG45684 anti-NANS antibody ICC/IF image

    Immunofluorescence: Hela stained with ARG45684 anti-NANS antibody at 5 μg/ml dilution.

  • ARG45684 anti-NANS antibody WB image

    Western blot: MCF-7 stained with ARG45684 anti-NANS antibody at 0.5 μg/ml dilution.

  • ARG45684 anti-NANS antibody WB image

    Western blot: Rat brain stained with ARG45684 anti-NANS antibody at 0.5 μg/ml dilution.