ARG63790
anti-NANOS1 antibody
anti-NANOS1 antibody for Western blot and Human
Developmental Biology antibody; Gene Regulation antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes NANOS1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NANOS1 |
| 抗原物种 | Human |
| 抗原 | C-SARDGPPGKKLR |
| 偶联标记 | Un-conjugated |
| 別名 | Nanos homolog 1; NOS1; SPGF12; EC_Rep1a; NOS-1 |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NANOS1 |
| 全名 | nanos homolog 1 (Drosophila) |
| 背景介绍 | This gene encodes a CCHC-type zinc finger protein that is a member of the nanos family. This protein co-localizes with the RNA-binding protein pumilio RNA-binding family member 2 and may be involved in regulating translation as a post-transcriptional repressor. Mutations in this gene are associated with spermatogenic impairment. [provided by RefSeq, Sep 2015] |
| 生物功能 | May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that associates with the 3'-UTR of mRNA targets. Capable of interfering with the proadhesive and anti-invasive functions of E-cadherin. Up-regulates the production of MMP14 to promote tumor cell invasion. [UniProt] |
| 研究领域 | Developmental Biology antibody; Gene Regulation antibody |
| 预测分子量 | 30 kDa |
检测图片 (1) Click the Picture to Zoom In
-
ARG63790 anti-NANOS1 antibody WB image
Western Blot: Human Testis lysate (35 µg protein in RIPA buffer) stained with ARG63790 anti-NANOS1 antibody at 0.3 µg/ml dilution.
