ARG46313
anti-NALP7 antibody
anti-NALP7 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NALP7 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NALP7 |
| 抗原物种 | Human |
| 抗原 | A 18 amino acid synthetic peptide within aa. 90 - 140 of human NALP7. |
| 偶联标记 | Un-conjugated |
| 別名 | NLRP7; NLR family, pyrin domain containing 7; NALP7; HYDM; PAN7; NALP7; NOD12; PYPAF3; CLR19.4; NACHT; LRR and PYD domains-containing protein 7; Nucleotide-binding oligomerization domain protein 12 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -363°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8WX94 Human NACHT, LRR and PYD domains-containing protein 7 |
|---|---|
| 基因名称 | NLRP7 |
| 全名 | NLR family, pyrin domain containing 7 |
| 背景介绍 | This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| 生物功能 | Inhibits CASP1/caspase-1-dependent IL1B secretion. [UniProt] |
| 预测分子量 | 112 kDa |
