概述

产品描述	Rabbit Polyclonal antibody recognizes N-RAS
反应物种	Hu
预测物种	Ms, Rat, Pig
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	N-RAS
抗原物种	Human
抗原	Human N-RAS recombinantprotein
偶联标记	Un-conjugated
Protein Full name	GTPase Nras
別名	NRAS; NRAS Proto-Oncogene, GTPase; N-Ras; Neuroblastoma RAS Viral (V-Ras) Oncogene Homolog; Neuroblastoma RAS Viral Oncogene Homolog; Transforming Protein N-Ras; GTPase NRas; V-Ras Neuroblastoma RAS Viral Oncogene Homolog; Proto-Oncogene GTPase; N-Ras Protein Part 4; EC 3.6.5.2; ALPS4; NRAS1; HRAS1; CMNS; KRAS; NCMS; NS6

应用说明

应用建议	应用 推荐稀释比 WB 1-2 μg/mL
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS containing 0.02% sodium azide
抗菌剂	0.02% sodium azide
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 4893 Human NRAS Swiss-port # P01111 Human GTPase NRas
基因名称	NRAS
全名	NRAS Proto-Oncogene, GTPase
背景介绍	This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
生物功能	Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
细胞定位	Cell membrane, Golgi apparatus, Membrane
预测分子量	21 kDa
翻译后修饰	Acetylation, Glycoprotein, Isopeptide bond, Lipoprotein, Methylation, Palmitate, Phosphoprotein, Prenylation, Ubl conjugation

检测图片 (1) Click the Picture to Zoom In